The top middle drawer is crammed full of overdue bills. The drawers on the right side are just nudie mags. Or at least that's the kind of thing Vergil assumes is in Dante's desk, but he doesn't need that in his heart, so they're just highly suggestive of being porn on the cover and totally empty inside.

The other side is just garbage. Random notes and receipts, but especially from pawn shops. There are a few notes bearing a different signature from the others, which is not so neat as Dante's, but if you squint it probably says Vergil. All of these seem to be contracts and records for devil hunting.